AutoCruitment

Runs paid digital campaigns (largely social and search) into a branded pre-screening funnel, then routes qualified referrals to sites. The pitch is speed: campaigns can be live within days of protocol sign-off, and sponsors see referral volume quickly.

Typically a campaign fee plus media spend, sometimes with per-referral or performance components. Publicly listed pricing is not available; ask for cost per randomized patient, not cost per referral.

Whatever the structure, convert it to cost per randomized patient before you compare proposals. Cost per referral is the number vendors prefer to quote and the number that tells you least.

• Fast campaign launch and high top-of-funnel referral volume
• Well-developed pre-screening technology and site-facing portal
• Markets dermatology and other visible-symptom indications heavily in its published case studies

• Referral volume is not enrollment. Ask for the referral-to-randomization ratio on studies like yours.
• Ask how many referrals per week your coordinators will be expected to work, and what happens if they cannot keep up.
• Its public materials centre on paid digital channels. Ask what share of referrals came from non-paid sources, and how performance held up when media costs rose.

Worth it when: Sponsors with a broad, self-identifying patient population and sites that have coordinator bandwidth to work a large referral queue.

Not worth it when: Ultra-rare indications where the addressable population cannot be reached economically through paid social.

• AntidoteMatches patients through a network of health advocacy and publisher partners.
• TrialfactsGuarantee-backed recruitment aimed at smaller and investigator-initiated studies.
• Clara HealthPatient-experience-led recruitment with concierge-style support.
• AcurianLarge-scale outreach using consumer data, part of a major CRO.

• AutoCruitment vs Antidote — Paid-media volume versus advocacy-sourced quality.
• AutoCruitment vs Clara Health — Referral volume versus navigated conversion.
• Trialfacts vs AutoCruitment — Guarantee-backed small studies versus scaled campaigns.

Ask for the referral-to-randomization ratio on three studies resembling yours, in the same indication and the same countries. If a vendor will not give it, that is the answer. If your enrollment forecast itself is the shaky part, our sister publication Rock Enroll covers forecasting and rescue in depth.