By specialty
Patient recruitment companies for rare disease
In rare disease the addressable population may be a few thousand people worldwide, so cost-per-click logic collapses. The vendors that work here reach patients through advocacy communities, treating specialists, and record mining rather than broad advertising.
- Patient community / registryAntidoteMatches patients through a network of health advocacy and publisher partners.Best for: Chronic and rare conditions with active advocacy groups, where credibility matters more than raw volume.
- Patient recruitment agencyClara HealthPatient-experience-led recruitment with concierge-style support.Best for: Burdensome protocols and rare indications where every candidate matters.
- Patient recruitment agencyAutoCruitmentDirect-to-patient digital recruitment with a proprietary pre-screener.Best for: Sponsors with a broad, self-identifying patient population and sites that have coordinator bandwidth to work a large referral queue.
- AI patient matchingDeep 6 AIMines clinical records, including unstructured notes, to find eligible patients.Best for: Oncology and precision-medicine trials with complex eligibility criteria.
- Patient recruitment agencyTrialfactsGuarantee-backed recruitment aimed at smaller and investigator-initiated studies.Best for: Academic groups, small biotechs, and single-site or few-site studies.